nci60wellstudied

=Well studied chemical classes=

The following chemical classes are considered well studied with respect to their ability to inhibit tumor cell growth. Compounds in these calsses will not be considered for testing in the 60 cell line screen unless additional information is provided that indicates that the particular compound has significantly different biological activity than the known members of the class.


 * 1)  Anthracyclines
 * 2)  Ellipticines
 * 3)  Nucleosides
 * 4)  Nitrogen mustards
 * 5)  Metal-containing compounds
 * 6)  a-Halo Carbonyl Compounds
 * 7)  Podophyllotoxins
 * 8)  Nitrosoureas
 * 9)  Antifolates
 * 10)  Actinomycins
 * 11)  9-Aminoacridines
 * 12)  Thiosemicarbazones
 * 13)  Camptothecins
 * 14)  Quarternary ammonium salts
 * 15)  Taxanes

Possible student project: provide chemical structures, examples, and some background on these classes.