JMGResearch_Results

>>>>>>>>>>> ==Results==

//DOPAL//
[|TLC of 3:1 methylenechloride methanol] with iodine to stain. [|HMR(with integration)]. [|HMR extension]. [|NMR 8.5-9.7] solubility: good in methanol, poor in methylene chloride [|HMR(w/o integration) D2O added] making 16B (note: the scale is way off)
 * Characterization after reaction**

//Ugi Reaction//
[|Piperonal](Used from same bottle in Exp076) [|Aniline] [|Boc-Gly-OH] [|tertbutylisocyanide]
 * Characterization of Starting Materials**

[|H NMR 1 hr 084A] [|H NMR 24 hrs 084B] [|H NMR 3 days 084C]
 * Part I: Imine Formation**

[|H NMR 2 hrs 084D]
 * PartII: Addition of Acid and Isocyanide**

[|ImineRxn overlay] [|UgiRxn overlay]
 * Overlays**

//Imine Reversal//
[|Piperonal] [|Tert-butylamine] [|2-morpholinoethyl isocyanide] [|Boc-Gly-OH]
 * Characterization of Starting Materials**

[|48PtI_A t=04mins] [|48PtI_B t=12mins] [|48PtI_C t=19mins] [|48PtI_D t=25mins] [|48PtI_E t=50mins] [|48PtI_F t=56mins] [|48PtI_G t=94mins]
 * Characterization of PartI: Imine Formation**

[|48PtII_A t=04mins] [|48PtII_B t=14mins] [|48PtII_C t=20mins]
 * Characterization of PartII - Addition of Boc-Gly-OH**

[|Overlay1] consists of HMRs piperonal, tertbutylamine, 12min,25min,50min,94mins from Part-I [|Overlay2] consists of HMRs piperonal, tertbutylamine, Boc-Gly-OH, A-C from Part-II and G from Part-I
 * Overlays**

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