Exp128

=Objective= To check the stability of the furan ring of [|acetamide of 5-methylfurfurylamine] from Exp078, in TFA to investigate [|the behavior of furan containing Ugi products].

=Procedure= A solution of [|acetamide of 5-methylfurfurylamine] (153mg, 1mmol) (78C) and pure TFA (1mL) in a round bottom flask, with a condenser was heated for about 30 min under N2.

=Results=

[|HNMR of 78C]
 * 128A** ([|+TFA 30min reflux])

=Discussion=

=Conclusion= The experiment was aborted. There was no initial HNMR taken to compare to after refluxing.

=Log=

2007-08-20
17:15 Set up reflux, added TFA (1000uL), acetamide (153mg) and stirrer 17:20 Started heating solution, 2 bubbles/sec of nitrogen 17:22 Reflux began - 5+ drops/sec 17:23 Turned down heat until refluxed at 2 drops/sec 18:00 Took off heat 18:30 Obtained HNMR of solution (**128A**)