Exp259



=Objective= To reapeat UCExp064 To synthesize a Ugi adduct from [|3,4-dimethoxybenzaldehyde], [|5-methylfurfurylamine], [|Benzylisocyanide] and [|Boc-Gly-OH] in methanol using Ugi 4CR. =Procedure= Dissolved [|3,4-dimethoxybenzaldehyde] (Veratradlehyde) (332mg, 2mmol) and [|5-methylfurfurylamine](5-MFA) (244uL, 2.2mmol, 10% excess ) in 4mL methanol-d4 in a 4mL volumetric flask, immediately transferred the contents to a 25mL Erlenmeyer flask, The reaction is allowed to sit for about 6 hours without stirring to form the imine. MS obtained. [|Nominal mass] [|High Res] [|Elemental analysis] [|High Res] [|MS- pdf] [|Exp064C-IR] Synthesized UCExp064C, successfully. 2010-05-24 Dissolved 332mg (2mmol) of veratraldehyde in methanol, added furfurylamine (244uL), boc glycine 350mg, 2mmol) and [|Benzylisocyanide](240uL, 2mmol). Left it to react over night. 2010-05-23 Obtained ppt, filtere, washed with methanol three times. Dried under vaccum oven. Obtained NM and IR MS obtained. [|Nominal mass] [|High Res] [|Elemental analysis] [|High Res] [|MS- pdf] [|Exp064C-IR]
 * Conclusion**
 * Log**