Exp034

= = = = =Objective= To obtain a Ugi product using [|phenylacetaldehyde], 5-[|methylfurfurylamine], [|Boc-Gly-OH], and [|2-morpholinoethyl isocyanide].

=Procedure= To an NMR tube was added [|phenylacetaldehyde] (111 uL, 1 mmol) and [|5-methylfurfurylamine](111 uL, 1 mmol) and allowed to sit for 10minutes after mixing. [|Boc-Gly-OH] (0.175 g, 1 mmol), [|2-morpholinoethyl isocyanide] (137 uL, 1 mmol) and CDCl3 (641 uL) were then added and mixed to bring volume to approximately 1mL.

=Results=

Characterization of 34A-T1 (6.5h)
HMR CMR

=Discussion=

=Conclusion=

=Log=

2006-10-23
13:10 Added [|phenylacetaldehyde] and [|5-methylfurfurylamine] to NMR tube. Inverted NMR tube three times. Noticed a white solid beginning to form. 13:20 (t=10min) Added [|Boc-Gly-OH] and [|2-morpholinoethyl isocyanide] along with CDCl3. White solid began to dissolve in solution. Inverted NMR tube three times. 19:45 Took proton and C13 NMRs **34A-T1 (6.5 h)**

=Tags= [|Phenylacetaldehyde], [|InChI=1/C8H8O/c9-7-6-8-4-2-1-3-5-8/h1-5,7H,6H2] [|Boc-Gly-OH][|InChI=1/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)] [|5-methylfurfurylamine][|InChI=1/C6H9NO/c1-5-2-3-6(4-7)8-5/h2-3H,4,7H2,1H3] [|2-morpholin ethyl isocyanide][|InChI=1/C7H12N2O/c1-8-2-3-9-4-6-10-7-5-9/h2-7H2] ugi034 [|InChI=1/C28H40N4O6/c1-21-10-11-23(37-21)20-32(25(33)19-30-27(35)38-28(2,3)4)24(18-22-8-6-5-7-9-22)26(34)29-12-13-31-14-16-36-17-15-31/h5-11,24H,12-20H2,1-4H3,(H,29,34)(H,30,35)]

media type="custom" key="7672"